What are enzyme detergent cleaners.

Enzyme Detergent Cleaners - Enzymatic Detergent Cleaners

The use of enzymes of various compositions and concentrations, in detergents is becoming common. Over half of all detergents presently available contain some level of enzymes. The enzymatic enzyme detergent industry is the largest single market for enzymes, at rate of 25 - 30% of total sales. Details of which enzymes are used within enzymatic enzyme detergents and the ways in which they are best used, are rarely been published. Enzymatic enzyme detergents should: remove proteinaceous bioburden, dissolve mineral encrustation, remove stains, and enhance the “passive layer” of stainless steel. Enzymatic enzyme detergents should be “free rinsing” to render a residue free surface and should be designed to condition the source water to counter the potential pitting and staining effects of hard water. The primary goal of cleaning is to remove soil (proteinaceous bioburden) which includes proteins, starches and lipids.

The Enzyme Detergent and Enzymatic Detergent Cleaner product claim of "fast acting enzyme" and "strongest enzyme" are usually erroneous. Enzymes all act at the same speed and are of equal strength. The application of the products and diluted concentrations determine the speed and the strength as it relates to cleaning outcomes.

Common misunderstandings exist pertaining to the application of Enzyme Detergent Enzyme Detergent Cleaners including the times and temperatures for optimal cleaning outcomes. There are parameters for the use of enzymatic enzyme detergents that can render a high probability of excellent cleaning outcomes.

It is commonly stated that enzyme detergent cleaners “clean”. Enzymes alone do not “clean”. The primary function of enzymes is to break down soil, usually proteinaceous bioburden. For a cleaning product to “clean” surfactants are necessary that will remove the soil from the surface. A combination of enzymes and detergents is necessary for “cleaning”. Enzymes and detergent combination products are referred to as “enzymatic enzyme detergents” or "all-in-one enzymatic enzyme detergents" .

The optimal temperature for maximum Enzyme Detergent Enzyme Detergent Cleaners cleaning performance peaks at 137 degrees Fahrenheit (58.33 degree Celsius). The detergent components typically peak performance at 185 degrees Fahrenheit (85 degree Celsius). The peak performance for the enzymes and the detergents represent the top of a bell curve with increasing and decreasing enzymatic enzyme detergent performance to each side the peak.

The Enzyme Detergent Enzyme Detergent Cleaners Dosage rate claims as to the cleaning results promised from very small dosage rates of enzymatic enzyme detergent can be misleading. Due to the wide variance of potential applications, the only dosage rates that can be attributed to a level of enzymatic enzyme detergent cleaning performance are those dosage rates that have been observed within your facility to render the cleaning outcomes required. The optimal enzymatic enzyme detergent dosage rate (amount diluted per quantity of carrier solution, usually ounces per gallon of neutral pH water) is a function of the types of enzymes and the concentration level of enzymes within the enzymatic enzyme detergent product. Detergents can render inferior performance with higher levels of concentration. Enzymes can render better performance at higher levels of concentration. To determine the optimal (lowest dosage with highest cleaning result) amount of enzymatic enzyme detergent to use, begin with the dosage recommended by the manufacture and then titrate the dosage higher or lower based on your cleaning outcomes. The cost of enzymatic enzyme detergents products is reconciled by their performance and your cost benefit analysis will be reconciled by the savings in the quantity of enzymatic enzyme detergents used.

The optimal application time for maximum Enzyme Detergent Enzyme Detergent Cleaners surgical instrument cleaning performance will depend of the level of soil hydration/encrustation, the amount of soil, and the mass of items being cleaned. Claims as to enzymatic enzyme detergent products “cleaning within minutes” are fallacious without specifics as to the above parameters.

Types of Enzyme Detergent Enzyme Detergent Cleaners potentially used within enzymatic enzyme detergents cleaning agents:

Lipase enzyme detergent cleaners: (to breakdown fat) to cleave fatty acid residue from the glycerol residue in a neutral fat or a phospholipid.

Amylase enzyme detergent cleaners: (to breakdown starch) to catalyze the hydrolysis of starch to sugar to produce carbohydrate derivatives.

Carbohydrase enzyme detergent cleaners: (to breakdown starch to a lower level) to catalyze the hydrolysis of higher carbohydrates to lower forms

Protease enzyme detergent cleaners: (breakdown blood) including the proteinases and peptidases, to catalyze the hydrolytic breakdown of proteins.

The use of Enzyme Detergent Enzyme Detergent Cleaners allows lower temperatures and shorter periods of mechanical instrument cleaning to be employed, often after a preliminary period of soaking. In general, enzyme detergents remove protein from clothes soiled with blood, milk, sweat, grass, etc. far more effectively than non-enzyme detergents. At present only proteases and amylases are commonly used. Although a wide range of lipases is known, it is only very recently that lipases suitable for use in detergent preparations have been deployed.

Enzyme Detergent Cleaners

enzymatic detergent cleaners

enzyme detergent cleaners cleaning time.

enzyme detergent cleaners cost/benefit.

enzyme detergent cleaners applications.

enzyme detergent cleaners sources.

enzyme detergent cleaners optimal temperatures

Enzymatic enzyme detergents must be cost-effective and safe to use.

Early attempts to use proteases floundered because users developed hypersensitivity. This was combated by developing dust-free granulates (about 0.5 mm in diameter) in which the enzyme is incorporated into an inner core, containing inorganic salts (e.g. NaCI) and sugars as preservative, bound with reinforcing, fibers of carboxymethyl cellulose or similar protective colloid. This core is coated with inert waxy materials made from paraffin oil or polyethylene glycol plus various hydrophilic binders, which later disperse in the wash. This combination of materials both prevents dust formation and protects the enzymes against damage by other detergent components during storage. It has been reported that spraying enzymatic enzyme detergent cleaning products has resulted in respiratory irritations. It is suspected that this is due to the enzyme aerosols. Applying the enzymatic enzyme detergent in a liquid of foam state should avoid this potential complication.

The composition of an Enzyme Detergent Enzyme Detergent Cleaners:

Constituent Composition (%)

Sodium tripolyphosphate (water softener, loosens dirt) 38.0%

Sodium alkane sulphonate (surfactant) 25.0%

Sodium perborate tetrahydrate (oxidising agent) 25.0%

Soap (sodium alkane carboxylates) 3.0%

Sodium sulphate (filler, water softener) 2.5%

Sodium carboxymethyl cellulose (dirt-suspending agent) 1.6%

Sodium metasilicate (binder, loosens dirt) 1.0%

Bacillus protease (3% active) 0.8%

Fluorescent brighteners 0.3

Foam-controlling agents Trace

Perfume (optional) Trace to cover potentially unacceptable aromas

Coloring (optional) Trace to provide visual evidence that product is present

Water to 100%

A recent trend is to reduce the phosphate content within Enzyme Detergent and Enzymatic Detergent Surgical Instrument Cleaning used for environmental reasons. It may be replaced by sodium carbonate plus extra protease. There is no reason that correlates with product efficacy for an enzymatic enzyme detergent to be other than "green".

The enzymes used for Enzyme Detergent Enzyme Detergent Cleaners are produced using species of Bacillus, mainly by just two companies. Novo Industri A/S produce and supply three proteases, Alcalase, from B. licheniformis, Esperase, from an alkalophilic strain of a B. licheniformis and Savinase, from an alkalophilic strain of B. amyloliquefaciens (often mistakenly attributed to B. subtilis). GistBrocades produce and supply Maxatase, from B. licheniformis. Alcalase and Maxatase (both mainly subtilisin) are recommended for use at 10-65°C and pH 7-10.5. Savinase and Esperase may be used at up to pH 11 and 12, respectively. The a-amylase supplied for detergent use is Termamyl, the enzyme from B. licheniformis which is also used in the production of glucose syrups. a-Amylase is particularly useful in washing glassware and with de-starching detergents.

Enzyme Detergent Enzyme Detergent Cleaners remove stains: preparations in a non-ionic surfactant are available for formulating in liquid 'spotting' concentrates, and are typically used for removing stubborn stains. Preparations containing both Termamyl and Alcalase are produced. Termamyl is sufficiently resistant to proteolysis to retain activity long enough to fulfill its function.

It should be noted that all the enzymatic enzyme detergent proteolytic enzymes described are fairly non-specific serine endoproteases, giving preferred cleavage on the carboxyl side of hydrophobic amino acid residues but capable of hydrolysing most peptide links. They convert their substrates into small, readily soluble fragments which can be removed easily from fabrics. Only serine protease; may be used in enzymatic enzyme detergent formulations: thiol proteases (e.g. papain) would be oxidized by the bleaching agents, and metalloproteases (e.g. thermolysin) would lose their metal cofactors due to the reaction with the water softening agents or hydroxyl ions.

There are opportunities to extend the use of Enzyme Detergent Enzyme Detergent Cleaners. The recent availability of a suitable lipase may increase the quantities of enzymes employed. There are, perhaps, opportunities for enzymes such as glucose oxidase, lipoxygenase and glycerol oxidase as means of generating hydrogen peroxide in situ. Added peroxidases may aid the bleaching efficacy of this peroxide.

The real cost of Enzyme Detergent Enzymatic Detergent Cleaning products is reconciled by their performance and your cost benefit analysis will be reconciled by the savings in the quantity of enzymatic enzyme detergents you use.

John Temple yourCEBA, ergo-Logistics

Surgical Instrument Cleaner

Surgical Instrument Washers

Experience optimal surgical instrument washer performance.